Skip to content

EGF Day Serum

A lightweight, oil-free, anti-aging face serum with Barley EGF proteins designed for everyday use to restore younger-looking skin with pure ingredients, boost hydration and provide a silky-smooth finish - an ideal base for makeup. Our Barley EGF is a moisture-binding and skin-rejuvenating protein, that helps support the skin’s natural collagen production, keeping skin looking smooth, healthy, and youthful.

or 4 interest free payments of $38.75 with

Features and Benefits

Refreshing Anti-Aging Day Gel Serum with Barley EGF

This innovative, plant-based growth factor serum is designed for daily use, as a part of an EGF skincare routine, and is oil-free, non-greasy, and not heavy or sticky. Address the visible signs of aging with Barley EGF – a skin-rejuvenating, moisture-binding, signaling protein – the first of its kind to be produced in plants. The EGF Day Serum has been shown to boost hydration, reduce the appearance of wrinkles and fine lines, and rejuvenate the complexion. Experience a clean skincare formula containing only 10 ingredients for purity and maximum efficacy.

  • Boosts Skin Hydration
  • Reduces the Appearance of Wrinkles and Fine Lines
  • Instantly Enhances the Complexion, and Evens Skin Tone
  • Silky-Smooth Finish, Perfect Under Makeup
  • Suitable for All Skin Types
  • Only 10 Ingredients
  • Oil-free, Fragrance-free, Alcohol-free, Paraben-Free, and Gluten-Free
  • Dermatologically tested

Size: 30 mL/ 0.5 fl.oz.

Key Ingredients

Barley EGF – A moisture-binding and skin-rejuvenating signaling protein, and the first of its kind to be produced in plants by BIOEFFECT scientists. Barley EGF promotes water retention, reducing loss of fluids from the skin. Increased moisture levels help maintain skin thickness and appearance of density, reducing the depth of wrinkles. Barley EGF helps support the skin’s natural collagen production to visibly improve appearance of skin density and minimize the appearance of fine lines and wrinkles.

Hyaluronic Acid – A vital substance naturally found in skin. It is critical for maintaining skin hydration. Known for its incredible capacity to attract and hold vast amounts of moisture. Hydrates and plumps the skin.

Glycerin – Powerful plant-based humectant that pulls moisture into the skin, while smoothing and conditioning the skin’s surface.

Icelandic Water – Clean, soft, and pure, as it is geologically filtered through layers of inert volcanic lava, with a low concentration of hard minerals such as calcium and magnesium.

Full Ingredient List


For external use only. Use only as directed. If irritation occurs, consult a dermatologist.

Real, Proven Results

In-house scientific efficacy study using the VISIA Skin Analysis System with participants using the EGF Day Serum twice daily for 3 months.

  • Up to 144%increase in skin hydration
  • Up to 49%decrease in wrinkles appearance
BeforeAfter 90 days

Maximize Your Skincare Routine

Barley EGF can do its best work in a moisture-rich environment. To maximize results, incorporate into an everyday BIOEFFECT EGF skincare routine.

Pair with:

  • EGF Essence is inspired by Asian skincare that uses these ‘miracle waters’ to boost hydration and prepare the skin to receive a serum.
  • Imprinting Hydrogel Mask delivers a powerful layer of moisture and creates a barrier on the skin for added skin benefits.

Info sheet


BIOEFFECT® EGF Day Serum is an age-defying serum specifically developed for daytime use. It reduces the appearance of fine lines and wrinkles, maximizes radiance, restores the skin’s moisture balance and provides a smooth finish, an ideal base for makeup.

• Reduces appearance of wrinkles

• Maximizes radiance and tone

• Restores skin density and firmness

• Ideal base for makeup

Directions for use: In the morning, apply 1-2 pumps to the face and neck on clean skin. Allow the serum to absorb completely for a approx. 3-5 minutes before applying makeup or sunscreen.

BIOEFFECT EGF Day Serum is suitable for all skin types and is fragrance-, alcohol- and oil-free. For very sensitive skin, test first on a small patch of skin for three days before full application. If you have a medical history of skin disorders/diseases, please consult a physician before using BIOEFFECT EGF Day Serum.

Allergy information: Product contains barley.

Avoid direct contact with eyes. In case of contact, rinse thoroughly with warm water. Keep out of reach of children. For external use only. Keep out of direct sunlight. Store at room temperature or below.

This Product is Pure, Green and Clean

How To Use

For best results apply 1-2 pumps to cleansed, fresh skin on the face, neck, and décolleté. Wait 3-5 minutes before applying a moisturizer, sunscreen, or makeup.

Pair with


4 / 55 Reviews
5 / 5

Love this product

I love the way this serum makes my skin feel. However I have noticed those tiny little white nodules under the skin since I have been using this serum. When that happens, I take a short break from the serum and focus on my prescription wrinkle cream, which seems to clear up the white bumps.

Bottom line: Yes, I would recommend this to a friend
3 / 5

This one was a miss

I love every BioEffect product EXCEPT the exfoliating cleanser and this. It feels really nice and the hydration is great (I don't need anything on top of this serum), however it peels and pills like crazy under makeup, or even if you massage it in too long. I pulled the trigger on the full size and now I'm just trying to use it up on days I don't apply anything on top of it, to avoid the peeling. Hopefully BE reformulates this sometime because it does have potential!

5 / 5


I can't truly convey how incredible this makes my skin feel. Like a brand new skin, silky and smooth! I want a bottle big enough for my entire body!

Bottom line: Yes, I would recommend this to a friend
5 / 5


Love the consistency I use this in the morning like a primer. Huge difference in my skin. You have to wait at least 10 minutes after applying it to put makeup or sunscreen on in the morning. Highly recommend

Bottom line: Yes, I would recommend this to a friend
2 / 5


This product was included a set I ordered from the site. I had high hopes for this product given how wonderfully my skin reacted to the 30 day treatment. Unfortunately, this pilled under both my makeup and sunscreen (even if I let it set for 20 minutes) which makes it useless to me as a daytime serum. I'll stick with the original serum twice daily instead. It's thick and moisturizing but does leave a slightly tacky residue. Also, I've never received a complimentary sample in either of my orders despite the website's claim to send them with all orders.