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EGF Serum

Award-winning, age-defying serum with Barley EGF to reduce the appearance of wrinkles and fine lines, boost hydration, and restore younger-looking skin with only 7 pure ingredients. Our Barley EGF is a moisture-binding and skin-rejuvenating protein, that helps support the skin’s natural collagen production and is essential for keeping skin looking smooth, healthy, and youthful.

Features and Benefits

The First Age-Defying Serum with Barley EGF
A groundbreaking age-defying serum designed to address the visible signs of ageing with Barley EGF – a skin-rejuvenating, moisture-binding, signaling protein – the first of its kind to be produced in plants. This award-winning growth factor serum has been shown to significantly reduce the appearance of wrinkles and fine lines, rejuvenate the complexion, and increase skin’s moisture level with just 2-4 drops. Experience a clean skincare formula containing only 7 ingredients for purity and maximum efficacy.

  • Visible Reduction in the Appearance of Wrinkles and Fine Lines
  • Boosts Hydration and Moisture Retention
  • Visibly Smoother, Plumper, and Firmer Skin
  • Instantly Enhances the Complexion and Evens Skin Tone
  • Suitable for All Skin Types
  • Only 7 Ingredients
  • Only 2-4 Drops Needed per Application
  • Oil-free, Fragrance-free, Alcohol-Free and Gluten-Free
  • No Preservatives Added
  • Hypoallergenic

Size: 5 mL/ 0.17 fl.oz. and 15 mL/ 0.5 fl.oz.

Key Ingredients

Barley EGF – Moisture-binding and skin-rejuvenating signaling protein. The first of its kind to be produced in plants by BIOEFFECT scientists to combat the visible effects from the loss of Epidermal Growth Factors found in our skin naturally. Barley EGF helps support the skin’s natural collagen production and is essential for keeping skin looking smooth, healthy, and youthful.

Hyaluronic Acid – A vital substance naturally found in skin. It is critical for maintaining skin hydration. Known for its incredible capacity to attract and hold vast amounts of moisture. Hydrates and plumps the skin.

Glycerin – Powerful plant-based humectant that pulls moisture into the skin, while smoothing and conditioning the skin’s surface.

Icelandic Water – Clean, soft, and pure, as it is geologically filtered through layers of inert volcanic lava, with a low concentration of hard minerals such as calcium and magnesium.

Full Ingredient List

Glycerin, Water (Aqua), Sodium Hyaluronate, Tromethamine, Sodium Chloride, Barley (Hordeum Vulgare) Seed Extract, Egf (Barley Sh-oligopeptide-1)

For external use only. Use only as directed. If irritation occurs, consult a dermatologist.

Real, Proven Results

In-house scientific efficacy study using the VISIA Skin Analysis System where participants used EGF Serum twice, daily for 3 months.

  • Up to 63%reduction in the appearance of wrinkles and fine lines
  • Up to 68%improvement in the appearance of skin elasticity, skin looks and feels firmer
  • Up to 132%increase in skin hydration
BeforeAfter 90 days

Maximise Your Skincare Routine

Barley EGF can do its best work in a moisture-rich environment. To maximise results, incorporate into an everyday BIOEFFECT skincare routine.

Pair with:

  • EGF Essence is inspired by Asian skincare that uses these ‘miracle waters’ to boost hydration and prepare the skin to receive a serum.
  • Imprinting Hydrogel Mask delivers a powerful layer of moisture and creates a barrier on the skin for added skin benefits.

Info sheet


BIOEFFECT® EGF SERUM is an award-winning age-defying serum to rejuvenate the skin and increase hydration. Prevents and tackles visible signs of skin aging and maintains skin's healthy condition with only 7 ingredients.

• Minimizes the appearance of fine lines and wrinkles

• Boosts hydration and moisture retention

• Renews, revives, and restores the skin

• Contains only 7 ingredients

Directions for use: Apply 2-4 drops of Growth Factor Serum to face, neck, and décolleté. Can be used morning and night, on its own or paired with other BIOEFFECT products for added benefit.

BIOEFFECT EGF SERUM is suitable for all skin types and is fragrance-, alcohol- and oil-free.

For very sensitive skin, test first on a small patch of skin for three days before full application. If you have a medical history of skin disorders/diseases, please consult a physician before using BIOEFFECT EGF SERUM.

Allergy information: Product contains barley.

Avoid direct contact with eyes. In case of contact, rinse thoroughly with warm water.
Keep out of reach of children. For external use only. Keep out of direct sunlight. Store at room temperature or below.

This Product is Pure, Green and Clean

How To Use

For best results, apply 2-4 drops of Growth Factor Serum to the face, neck, and décolleté, twice per day. Apply in the morning and wait 3-5 minutes before applying a moisturiser, sunscreen, or makeup. Apply in the evening to clean skin for advanced skin repair while you sleep.

Pair with

Frequently Asked Questions.


4.45 / 558 Reviews
5 / 5

Bioeffect sérum

I use Bioeffect 3 years and I love the products works for me good anti-aging and good and clean line no oil no perfume no alcohol I use every day and night and my skin is very young I am 55 and my skin not Thanks bioeffect

5 / 5

Absolutely Amazing!

I love the BioEffect EGF Serum! I have normal to oily skin prone to hormonal breakouts around my jawline. This serum has helped control the occasional breakout and does not clog my pores. My skin is clear and glowing. I would highly recommend the EGF serum.

5 / 5

Used it for 6 weeks and got carded again

I use this product once a day, 2 drops and it is more than enough to cover my face. I have nothing but good things to say. I haven't been carded in like five years and suddenly I'm getting asked for my ID again, I think that says it all.

Tracie S
5 / 5


Ok I got this as a free gift with several other things…I've never heard of it..I tried it the first time and was completely blown away..I cleansed first, use my toner and thought hey I'm gonna try this cute tiny bottle serum..put it on my face and it just feel so amazing ..I quickly looked it up and am even more blown away by what this little is! AMAZING! Try it! It's gonna be my new staple! I don't even feel like I need a moisturizer after so incredibly hydrating leaves skin super smooth!

5 / 5

it really works, after just few applies

i got a sample while i was in Iceland and omg now im addicited ;) Removed all fist signs of wrinkles like magic.

Bottom line: Yes, I would recommend this to a friend